Abstract Background Pinpointing genetic impacts on DNA methylation can improve our understanding of pathways that underlie gene regulation and disease risk.Results We report heritability and methylation quantitative here trait locus (meQTL) analysis at 724,499 CpGs profiled with the Illumina Infinium MethylationEPIC array in 2358 blood samples from
Borrelia burgdorferi and Borrelia miyamotoi are tick-vectored zoonotic pathogens maintained in wildlife species.Tick populations are establishing in new areas globally in response to climate change and other factors.New Brunswick is a Canadian maritime province at the advancing front of tick population establishment and has seen increasing numbers
Cultured preadipocytes derived from the stromal-vascular fraction of adipose tissue have been shown to accumulate sufficient triglycerides to assume adipocyte morphology when exposed to high concentrations of very low density lipoprotein.Since these cells synthesize and secrete lipoprotein lipase it was of interest to determine whether the accumula